Protease DEGRADOMICS
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Publications

Publications by all team members while working at ZEA-3 Analytics. * corresponding author, # equal contribution, § shared senior author. Please check our team page for individual publication lists. 

2018

  1. González de San Román E#, Bidmon HJ#, Malisic M, Susnea I, Küppers A, Hübbers R, Wree A, Nischwitz V, Amunts K*§, Huesgen PF*§. Molecular composition of the human primary visual cortex profiled by multimodal mass spectrometry imaging. Brain Structure and Function, online early April 10, 2018, doi: 10.1007/s00429-018-1660-y
  2. Demir F#, Niedermaier S#, Villamor JG, Huesgen PF*. Quantitative proteomics in plant protease substrate identification. New Phytol 218(3):936-943. doi: 10.1111/nph.14587. Epub 2017 May 11. Review.

2017

  1. Rinschen MM*, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF*§, Benzing T*§. N-Degradomic analysis reveals a proteolytic network processing the podocyte cytoskeleton. J Am Soc Nephrol, 28: 2867-2878, doi: 10.1681/ASN.2016101119. See also comment in Nat Rev Nephrol 13(10):596. doi: 10.1038/nrneph.2017.115.
  2. Demir F, Niedermaier S, Kizhakkedathu JN, Huesgen PF*. Profiling of Protein N-Termini and Their Modifications in Complex Samples. Methods Mol Biol, 574:35-50. doi: 10.1007/978-1-4939-6850-3_4.

2016

  1. Biniossek ML, Niemer M, Maksimchuk K, Mayer B, Fuchs J, Huesgen PF, McCafferty DG, Turk B, Fritz G, Mayer J, Haecker G, Mach L, Schilling O. Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics. Mol Cell Proteomics, 15:2515-24. doi: 10.1074/mcp.O115.056671.
  2. Susnea I and Weiskirchen R. Trace metal imaging in diagnostic of hepatic metal disease. Mass Spec Rev, 35:666-686. doi: 10.1002/mas.21454.
  3. Leal AR, Cruz R, Bur D, Huesgen PF, Faro R, Manadas B, Wlodawer A, Faro C,  Simões I. Enzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanella denitrificans. Sci Rep 6:23869. doi: 10.1038/srep23869
  4. Eckhard U#, Huesgen PF#, Schilling O#, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, auf dem Keller U, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, Rodriguez D, Starr AE, Wang Y, Overall CM. Active site specificity profiling datasets of matrix metalloproteinases (MMP) 1, 2, 3, 7, 8, 9, 12, 13, 14. Data Brief 7:299-310. doi:10.1016/j.dib.2016.02.036
  5. Eckhard U#, Huesgen PF#, Schilling O#, Bellac CL, Butler GS, Cox JH, Dufour A, Goebeler V, Kappelhoff R, auf dem Keller U, Klein T, Lange PF, Marino G, Morrison CJ, Prudova A, Rodriguez D, Starr AE, Wang Y, Overall CM. Active Site Specificity of the Matrix Metalloproteinase Family: Proteomic Identification of 4,300 Cleavage Sites by Nine MMPs explored with Structural and Synthetic Peptide Cleavage Analyses. Matrix Biol 49:37-90. doi:10.1016/j.matbio.2015.09.003

2015

  1. Zelanis A, Huesgen PF, Oliveira AK, Tashima AK, Serrano SM and Overall CM. Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites. J Proteomics 113:260-7. doi: 10.1016/j.jprot.2014.10.002.
  2. Huesgen PF, Lange PF, Rogers LD, Solis N, Eckhard U, Kleifeld O, Goulas T, Gomis-Rüth FX and Overall CM. LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification. Nat Methods 12:55-8. doi: 10.1038/nmeth.317

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  • Home
  • Team
    • Alumni and Visitors
    • Open Positions
  • Research
    • Proteomics tools and methods
    • Plant degradomics
    • Proteolytic processing in health and disease
    • Mass spectrometry imaging
  • Publications
  • Equipment
  • Contact
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